Griseofulvin: Phenobarbital appears to interfere with the absorption of orally administered griseofulvin, thus decreasing its blood level.The barbiturates are nonselective central nervous Gebilde depressants which are primarily used as sedative hypnotics and also anticonvulsants hinein subhypnotic doses. The barbiturates and their sodium salts are

Barbiturates appear to enhance the metabolism of exogenous corticosteroids probably through the induction of hepatic microsomal enzymes. Patients stabilized on corticosteroid therapy may require dosage adjustments if barbiturates are added to or withdrawn from their dosage regimen.Data are currently not available to evaluate the effect of these bar